A survey of attitudes towards methicillin-resistant Staphylococcus aureus bacteraemias amongst United Kingdom microbiologists | Zendy

Abid Hussain | Zendy; Susan Alleyne | Zendy; David R. Jenkins | Zendy

Open Access

A survey of attitudes towards methicillin-resistant Staphylococcus aureus bacteraemias amongst United Kingdom microbiologists

Author(s) -

Abid Hussain,

Susan Alleyne,

David R. Jenkins

Publication year - 2009

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkp456

Subject(s) - linezolid , daptomycin , tigecycline , vancomycin , medicine , methicillin resistant staphylococcus aureus , etest , staphylococcus aureus , antibiotics , intensive care medicine , microbiology and biotechnology , biology , bacteria , genetics

Methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infections (BSIs) in the UK are common and associated with significant morbidity and mortality. Vancomycin is the usual first-line therapy. However, vancomycin treatment of BSIs due to MRSA strains with vancomycin MICs of 1-2 mg/L is successful in <10% of cases. No consensus exists on when to use newer agents, particularly when vancomycin MICs are >1 mg/L. We therefore surveyed UK practices of the management of MRSA BSIs due to isolates with increased vancomycin MICs.

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