Open AccessSmaqnr, a new chromosome-encoded quinolone resistance determinant in Serratia marcescens
Author(s) -
C. Velasco,
José Manuel Rodríguez-Martínez,
A. Briales,
Paula Díaz de Alba,
Jorge Calvo,
Álvaro Pascual
Publication year - 2009
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkp424
Subject(s) - serratia marcescens , biology , microbiology and biotechnology , escherichia coli , gene , quinolone , nalidixic acid , southern blot , plasmid , genetics , antibiotics
A new pentapeptide repeat (PRP) protein, named SmaQnr, from the clinically relevant species Serratia marcescens, which decreased susceptibility to quinolones when expressed in Escherichia coli, is reported herein.
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