Fluconazole at subinhibitory concentrations induces the oxidative- and nitrosative-responsive genes TRR1, GRE2 and YHB1, and enhances the resistance of Candida albicans to phagocytes | Zendy

David M. Arana | Zendy; César Nombela | Zendy; Jesús Plá | Zendy

Open Access

Fluconazole at subinhibitory concentrations induces the oxidative- and nitrosative-responsive genes TRR1, GRE2 and YHB1, and enhances the resistance of Candida albicans to phagocytes

Author(s) -

David M. Arana,

César Nombela,

Jesús Plá

Publication year - 2009

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkp407

Subject(s) - candida albicans , microbiology and biotechnology , fluconazole , oxidative stress , corpus albicans , biology , hydrogen peroxide , oxidative phosphorylation , reactive oxygen species , in vitro , respiratory burst , chemistry , biochemistry , antifungal

To analyse the oxidative and nitrosative stress response in Candida albicans generated by fluconazole at subinhibitory concentrations, and the functional consequences of such a response for the interaction with phagocytic cells.

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