Open AccessTreatment outcome of invasive mould disease after sequential exposure to azoles and liposomal amphotericin B
Author(s) -
Oliver A. Cornely,
Johan Maertens,
Mark Bresnik,
Andrew J. Ullmann,
Ramin Ebrahimi,
Raoul Herbrecht
Publication year - 2009
Publication title -
the journal of antimicrobial chemotherapy/journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkp397
Subject(s) - amphotericin b , medicine , pharmacokinetics , intensive care medicine , pharmacology , antifungal , dermatology
To analyse the potential antagonism between azoles, which inhibit ergosterol synthesis, and polyenes, which bind directly to ergosterol in cell membranes, in patients receiving sequential azole-polyene treatment.