Open AccessRestricting ciprofloxacin-induced resistant variant formation in biofilm of Klebsiella pneumoniae B5055 by complementary bacteriophage treatment
Author(s) -
Vivek Verma,
Kusum Harjai,
Sanjay Chhibber
Publication year - 2009
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkp360
Subject(s) - klebsiella pneumoniae , ciprofloxacin , microbiology and biotechnology , bacteriophage , biofilm , klebsiella , biology , virology , bacteria , antibiotics , escherichia coli , gene , genetics
The in vitro efficacy of lytic bacteriophage as a therapeutic agent against Klebsiella pneumoniae biofilm, alone or in combination with ciprofloxacin, was studied. The pathogenic potential of the resistant variants formed during the treatment was evaluated.
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