Exposure of Escherichia coli and Salmonella enterica serovar Typhimurium to triclosan induces a species-specific response, including drug detoxification | Zendy

Andy M. Bailey | Zendy; Chrystala Constantinidou | Zendy; Alasdair Ivens | Zendy; M.I. Garvey | Zendy; Mark Webber | Zendy; N. G. Coldham | Zendy; Jon L. Hobman | Zendy; John Wain | Zendy; Martin J. Woodward | Zendy; Laura J. V. Piddock | Zendy

Open Access

Exposure of Escherichia coli and Salmonella enterica serovar Typhimurium to triclosan induces a species-specific response, including drug detoxification

Author(s) -

Andy M. Bailey,

Chrystala Constantinidou,

Alasdair Ivens,

M.I. Garvey,

Mark Webber,

N. G. Coldham,

Jon L. Hobman,

John Wain,

Martin J. Woodward,

Laura J. V. Piddock

Publication year - 2009

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkp320

Subject(s) - salmonella enterica , triclosan , microbiology and biotechnology , escherichia coli , serotype , salmonella , enterobacteriaceae , detoxification (alternative medicine) , biology , drug , bacteria , medicine , pharmacology , biochemistry , gene , alternative medicine , genetics , pathology

The use of triclosan within various environments has been linked to the development of multiple drug resistance (MDR) through the increased expression of efflux pumps such as AcrAB-TolC. In this work, we investigate the effect of triclosan exposure in order to ascertain the response of two species to the presence of this widely used biocide.

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