Open AccessCerebrospinal fluid impairs antimicrobial activity of fosfomycin in vitro
Author(s) -
Robert Sauermann,
Richard Schwameis,
Manfred Fille,
M. L. Camuz Ligios,
Markus Zeitlinger
Publication year - 2009
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkp261
Subject(s) - fosfomycin , cerebrospinal fluid , antimicrobial , in vitro , central nervous system , microbiology and biotechnology , antibiotics , medicine , chemistry , pharmacology , biology , pathology , biochemistry
Fosfomycin penetrates well into cerebrospinal fluid (CSF) and is considered for treatment of infections of the central nervous system (CNS). This study evaluated the influence of human CSF on the antimicrobial activity of fosfomycin.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom