Molecular characterization of macrolide resistance determinants [erm(B) and mef(A)] in Streptococcus pneumoniae and viridans group streptococci (VGS) isolated from adult patients with cystic fibrosis (CF) | Zendy

А. Тазуми | Zendy; Yasunori Maeda | Zendy; Colin E. Goldsmith | Zendy; Wilson A. Coulter | Zendy; Charlene Mason | Zendy; B.C. Millar | Zendy; Mark McCalmont | Zendy; Jackie Rendall | Zendy; J.S. Elborn | Zendy; Motoo Matsuda | Zendy; John E. Moore | Zendy

Open Access

Molecular characterization of macrolide resistance determinants [erm(B) and mef(A)] in Streptococcus pneumoniae and viridans group streptococci (VGS) isolated from adult patients with cystic fibrosis (CF)

Author(s) -

А. Тазуми,

Yasunori Maeda,

Colin E. Goldsmith,

Wilson A. Coulter,

Charlene Mason,

B.C. Millar,

Mark McCalmont,

Jackie Rendall,

J.S. Elborn,

Motoo Matsuda,

John E. Moore

Publication year - 2009

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkp213

Subject(s) - azithromycin , cystic fibrosis , microbiology and biotechnology , streptococcus pneumoniae , group a , group b , macrolide antibiotics , streptococcus , medicine , immunology , biology , erythromycin , antibiotics , bacteria , genetics

Although long-term use of azithromycin has shown a significant clinical improvement for patients with cystic fibrosis (CF), its long-term effect on the susceptibility of commensal flora within CF airways has not yet been examined. We therefore suggest that long-term use of azithromycin increases macrolide resistance in commensal streptococci.

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