Rapid decline in the efficiency of HIV drug resistance genotyping from dried blood spots (DBS) and dried plasma spots (DPS) stored at 37 C and high humidity | Zendy

J. Gerardo Garcı́a-Lerma | Zendy; A. McNulty | Zendy; Cheryl Jennings | Zendy; D. Huang | Zendy; Walid Heneine | Zendy; James W. Bremer | Zendy

Open Access

Rapid decline in the efficiency of HIV drug resistance genotyping from dried blood spots (DBS) and dried plasma spots (DPS) stored at 37 C and high humidity

Author(s) -

J. Gerardo Garcı́a-Lerma,

A. McNulty,

Cheryl Jennings,

D. Huang,

Walid Heneine,

James W. Bremer

Publication year - 2009

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkp150

Subject(s) - dried blood , spots , dried blood spot , genotyping , drug resistance , medicine , biology , chromatography , microbiology and biotechnology , chemistry , genotype , pathology , genetics , gene

Dried blood spots (DBS) and dried plasma spots (DPS) are considered convenient alternatives to serum and plasma for HIV drug resistance testing in resource-limited settings. We sought to investigate how extreme conditions could affect the short-term ability to amplify and genotype HIV from DBS.

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