Why empirical therapy?
Author(s) -
Jean Klášterský
Publication year - 2009
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkp075
Subject(s) - medicine , febrile neutropenia , antimicrobial , intensive care medicine , neutropenia , empirical treatment , occult , cancer therapy , sepsis , antibiotic therapy , cancer , antibiotics , chemotherapy , biology , alternative medicine , microbiology and biotechnology , pathology
Why empirical therapy? Because it works! Empirical antimicrobial therapy is a reasonable, pragmatic approach to limit the ominous threat of Gram-negative sepsis in febrile neutropenic cancer patients. Empirical treatment of occult fungal infection in patients with neutropenia and persistent fever, in spite of initial broad-spectrum antimicrobial coverage, is effective but the role of pre-emptive treatment remains to be established.
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