Saquinavir exposure in HIV-infected patients with chronic viral hepatitis
Author(s) -
José Moltó,
Josep M. Llibre,
Esteban Ribera,
Carlos Mínguez,
J. Sánchez del Río,
Enric Pedrol,
Gabriel Vallecillo,
Samandhy Cedeño,
Marta Valle,
C Miranda,
Eugènia Negredo,
B. Clotet
Publication year - 2009
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkp070
Subject(s) - saquinavir , ritonavir , medicine , gastroenterology , pharmacology , pharmacokinetics , virology , viral load , human immunodeficiency virus (hiv) , antiretroviral therapy
The aim of this study was to assess the influence of hepatitis B virus or hepatitis C virus co-infection and the extent of liver fibrosis on saquinavir and ritonavir pharmacokinetics in HIV-infected subjects without liver function impairment.
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