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Effect of long-term trimethoprim/sulfamethoxazole treatment on resistance and integron prevalence in the intestinal flora: a randomized, double-blind, placebo-controlled trial in children
Author(s) -
Elly L. van der Veen,
Anne GM Schilder,
Tim K. Timmers,
Maroeska M. Rovers,
Ad C. Fluit,
Marc J. M. Bonten,
Maurine A. Leversteinvan Hall
Publication year - 2009
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkp050
Subject(s) - trimethoprim , sulfamethoxazole , placebo , population , medicine , antibacterial agent , microbiology and biotechnology , integron , antibiotics , enterobacteriaceae , biology , antibiotic resistance , escherichia coli , pathology , environmental health , alternative medicine , biochemistry , gene
The aim of this study was to test the hypothesis that trimethoprim/sulfamethoxazole selects for integron-positive and multidrug-resistant Enterobacteriaceae in the intestinal flora.

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