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Comparative in vitro activity of REP3123 against Clostridium difficile and other anaerobic intestinal bacteria
Author(s) -
D. M. Citron,
Yumi A. Warren,
Kerin L. Tyrrell,
Virginia Merriam,
Ellie J. C. Goldstein
Publication year - 2009
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkp037
Subject(s) - microbiology and biotechnology , anaerobic bacteria , bacteria , anaerobic exercise , clostridium difficile , biology , clostridium , clostridiales , gram positive bacteria , antibacterial agent , gram negative bacteria , intestinal bacteria , antibiotics , escherichia coli , biochemistry , physiology , genetics , gene
The aim of this study was to determine the anaerobic spectrum of activity of REP3123, a novel diaryldiamine that inhibits bacterial methionyl-tRNA synthetases in Gram-positive bacteria.

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