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levofloxacin-resistant Streptococcus pneumoniae: a case–control study. Clin Infect Dis 2001; 32: 701–7. 6. Davies TA, Yee YC, Bush K et al. Effects of the 7-valent pneumococcal conjugate vaccine on U.S. levofloxacin-resistant Streptococcus pneumoniae. Microb Drug Resist 2008; 14: 187–96. 7. Ho PL, Que TL, Chiu SS et al. Fluoroquinolone and other antimicrobial resistance in invasive pneumococci, Hong Kong, 1995–2001. Emerg Infect Dis 2004; 10: 1250–7.

Mecillinam: a low-risk antimicrobial agent for induction of Clostridium difficile infection in an in vitro human gut model