Activity of oxazolidinone TR-700 against linezolid-susceptible and -resistant staphylococci and enterococci
Author(s) -
D. M. Livermore,
Shazad Mushtaq,
M. Warner,
N. Woodford
Publication year - 2009
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkp002
Subject(s) - linezolid , enterococcus faecium , 23s ribosomal rna , microbiology and biotechnology , enterococcus , agar dilution , minimum inhibitory concentration , staphylococcus aureus , enterococcus faecalis , antibiotics , chemistry , biology , bacteria , vancomycin , biochemistry , rna , gene , genetics , ribosome
TR-700 is the active moiety of TR-701 (DA-7157), a new oral/intravenous oxazolidinone prodrug. We examined its activity against linezolid-susceptible and -resistant staphylococci and enterococci.
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