Efficacy of telavancin against glycopeptide-intermediate Staphylococcus aureus in the neutropenic mouse bacteraemia model
Author(s) -
Sharath S. Hegde,
Stacey Difuntorum,
Robert Skinner,
J. Trumbull,
Kevin M. Krause
Publication year - 2009
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkp001
Subject(s) - vancomycin , staphylococcus aureus , spleen , glycopeptide , microbiology and biotechnology , medicine , antibacterial agent , bacteremia , antibiotics , immunology , biology , bacteria , genetics
The aim of the study was to compare the efficacies of telavancin and vancomycin against glycopeptide-intermediate Staphylococcus aureus (GISA) and heterogeneous vancomycin-intermediate S. aureus (hVISA) in a neutropenic murine bacteraemia model.
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