Functional relationship between bacterial cell density and the efficacy of antibiotics
Author(s) -
Klas I. Udekwu,
Nicholas F. Parrish,
Pierre Ankomah,
Fernando Baquero,
Bruce R. Levin
Publication year - 2009
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkn554
Subject(s) - antibiotics , daptomycin , ciprofloxacin , biology , staphylococcus aureus , microbiology and biotechnology , pharmacodynamics , vancomycin , population , bacteria , pharmacokinetics , medicine , pharmacology , genetics , environmental health
To determine the functional relationship between the density of bacteria and the pharmacodynamics of antibiotics, and the potential consequences of this inoculum effect on the microbiological course of antibiotic treatment of Staphylococcus aureus infections.
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