Open AccessImpact of slime dispersants and anti-adhesives on in vitro biofilm formation of Staphylococcus epidermidis on intraocular lenses and on antibiotic activities
Author(s) -
Azza M. Kadry,
Soliman I. Fouda,
Atef M. Shibl,
Ahmed Abu El-Asrar
Publication year - 2009
Publication title -
the journal of antimicrobial chemotherapy/journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkn533
Subject(s) - staphylococcus epidermidis , dispersant , biofilm , microbiology and biotechnology , antibiotics , adhesive , bacteria , chemistry , biology , staphylococcus aureus , organic chemistry , physics , layer (electronics) , optics , genetics , dispersion (optics)
Infectious endophthalmitis has occurred despite the use of antibiotics in irrigating solutions during implantation of intraocular lenses (IOLs). This infection is generally resistant to antibiotic therapy and, therefore, removal of the implant is necessary before eradication of the infection. This study was designed to assess the role of chosen dispersants and anti-adhesives in inhibiting Staphylococcus epidermidis hydrophobicity, adhesion, slime production and subsequently biofilm formation on IOLs.