Influence of liver fibrosis stage on plasma levels of efavirenz in HIV-infected patients with chronic hepatitis B or C | Zendy

Jean Luc Meynard | Zendy; Karine Lacombe | Zendy; J.M. POIRIER | Zendy; J. Legrand | Zendy; Laurence MorandJoubert | Zendy; PierreMarie Girard | Zendy

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Influence of liver fibrosis stage on plasma levels of efavirenz in HIV-infected patients with chronic hepatitis B or C

Author(s) -

Jean Luc Meynard,

Karine Lacombe,

J.M. POIRIER,

J. Legrand,

Laurence MorandJoubert,

PierreMarie Girard

Publication year - 2009

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkn531

Subject(s) - efavirenz , medicine , chronic hepatitis , liver fibrosis , stage (stratigraphy) , fibrosis , human immunodeficiency virus (hiv) , gastroenterology , hepatitis , hepatitis c , virology , immunology , viral load , antiretroviral therapy , virus , biology , paleontology

Liver function is a key component of efavirenz metabolism and might be altered in severe liver fibrosis induced by HIV/chronic hepatitis co-infection. However, data evaluating the impact of liver fibrosis stages on the plasma efavirenz level are lacking.

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