Effect of tunicamycin on Candida albicans biofilm formation and maintenance | Zendy

Christopher G. Pierce | Zendy; Derek P. Thomas | Zendy; José L. López-Ribot | Zendy

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Effect of tunicamycin on Candida albicans biofilm formation and maintenance

Author(s) -

Christopher G. Pierce,

Derek P. Thomas,

José L. López-Ribot

Publication year - 2008

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkn515

Subject(s) - tunicamycin , biofilm , candida albicans , microbiology and biotechnology , corpus albicans , glycosylation , biology , chemistry , bacteria , biochemistry , unfolded protein response , genetics , endoplasmic reticulum

Candida albicans is a common opportunistic pathogen of the human body and is the frequent causative agent of candidiasis. Typically, these infections are associated with the formation of biofilms on both host tissues and implanted biomaterials. As a result of the intrinsic resistance of C. albicans biofilms to most antifungal agents, new strategies are needed to combat these infections.

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