Efficacy of telavancin in the treatment of methicillin-resistant Staphylococcus aureus osteomyelitis: studies with a rabbit model | Zendy

Liyan Yin | Zendy; Jason H. Calhoun | Zendy; Tim Thomas | Zendy; Eric Wirtz | Zendy

Open Access

Efficacy of telavancin in the treatment of methicillin-resistant Staphylococcus aureus osteomyelitis: studies with a rabbit model

Author(s) -

Liyan Yin,

Jason H. Calhoun,

Tim Thomas,

Eric Wirtz

Publication year - 2008

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkn490

Subject(s) - linezolid , vancomycin , osteomyelitis , staphylococcus aureus , medicine , methicillin resistant staphylococcus aureus , antibiotics , surgery , microbiology and biotechnology , biology , bacteria , genetics

Staphylococcus aureus is the most common pathogen isolated in osteomyelitis. This study evaluated the efficacies of telavancin (an investigational, rapidly bactericidal lipoglycopeptide with a multifunctional mechanism of action against Gram-positive bacteria), vancomycin and linezolid in a rabbit methicillin-resistant S. aureus (MRSA) osteomyelitis model.

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