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High rate of early virological failure with the once-daily tenofovir/lamivudine/nevirapine combination in naive HIV-1-infected patients
Author(s) -
D. Rey,
Bruno Hoën,
P. Chavanet,
MariePaule Schmitt,
Guillaume Hoizey,
P. Meyer,
Gilles Peytavin,
Bruno Spire,
Clotilde Allavena,
Myriam Diemer,
T. May,
J.L. Schmit,
Michel Duong,
Vincent Cálvez,
Jean-Marie Lang
Publication year - 2008
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkn471
Subject(s) - nevirapine , lamivudine , zidovudine , medicine , viral load , resistance mutation , reverse transcriptase inhibitor , gastroenterology , virology , abacavir , reverse transcriptase , human immunodeficiency virus (hiv) , biology , viral disease , virus , antiretroviral therapy , hepatitis b virus , rna , biochemistry , gene
The combination of one non-nucleoside reverse transcriptase inhibitor (NNRTI) with two nucleoside reverse transcriptase inhibitors is a validated first-line antiretroviral (ARV) therapy. The once-daily combination of lamivudine, tenofovirDF and nevirapine has not been evaluated in a clinical trial.

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