Rapid genotypic assays to identify drug-resistant Mycobacterium tuberculosis in South Africa | Zendy

Joanna C. Evans | Zendy; Michael C. Stead | Zendy; Mark P. Nicol | Zendy; Heidi Segal | Zendy

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Rapid genotypic assays to identify drug-resistant Mycobacterium tuberculosis in South Africa

Author(s) -

Joanna C. Evans,

Michael C. Stead,

Mark P. Nicol,

Heidi Segal

Publication year - 2008

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkn433

Subject(s) - inha , isoniazid , genotype , biology , mycobacterium tuberculosis , virology , drug resistance , tuberculosis , rifampicin , microbiology and biotechnology , genetics , medicine , antibiotics , gene , pathology

Molecular assays to detect drug resistance in Mycobacterium tuberculosis are more rapid than standard drug susceptibility testing. To evaluate the efficacy of such assays in this setting, the GenoType MTBDRplus assay (HAIN Lifescience) and multiplex allele-specific PCR assays were carried out.

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