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In vitro activity of fusidic acid and mupirocin against coagulase-positive staphylococci from pets
Author(s) -
Anette Loeffler,
Stephen Baines,
Mark A. Toleman,
D. Felmingham,
S. K. Milsom,
E. A. Edwards,
D. H. Lloyd
Publication year - 2008
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkn398
Subject(s) - fusidic acid , mupirocin , staphylococcus pseudintermedius , microbiology and biotechnology , antibiotics , staphylococcus aureus , staphylococcal infections , agar dilution , methicillin resistant staphylococcus aureus , biology , medicine , staphylococcus , minimum inhibitory concentration , bacteria , genetics
Methicillin-resistant Staphylococcus aureus (MRSA) and multiresistant Staphylococcus pseudintermedius (MRSP) have emerged as important pathogens in animal infections. Associated therapeutic problems and the zoonotic potential of staphylococci have renewed interest in topical antibiotics for treatment and carrier decolonization. Fusidic acid and mupirocin are used topically in humans and animals but resistant strains isolated from people are increasing. This study investigates the in vitro activity of fusidic acid and mupirocin against coagulase-positive staphylococci from pets.

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