Pre-medication practices and incidence of infusion-related reactions in patients receiving AMPHOTEC®: data from the Patient Registry of Amphotericin B Cholesteryl Sulfate Complex for Injection Clinical Tolerability (PRoACT) registry | Zendy

David L. Paterson | Zendy; Kristin David | Zendy; Mirando Mršić | Zendy; Petr Cetkovský | Zendy; Xinhua Weng | Zendy; Jaroslav Štěrba | Zendy; Gregerly Krivan | Zendy; D Bošković | Zendy; Min-qiang Lu | Zendy; Li Zhu | Zendy

Open Access

Pre-medication practices and incidence of infusion-related reactions in patients receiving AMPHOTEC®: data from the Patient Registry of Amphotericin B Cholesteryl Sulfate Complex for Injection Clinical Tolerability (PRoACT) registry

Author(s) -

David L. Paterson,

Kristin David,

Mirando Mršić,

Petr Cetkovský,

Xinhua Weng,

Jaroslav Štěrba,

Gregerly Krivan,

D Bošković,

Min-qiang Lu,

Li Zhu

Publication year - 2008

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkn394

Subject(s) - tolerability , amphotericin b , medicine , incidence (geometry) , adverse effect , pharmacology , surgery , antifungal , physics , dermatology , optics

Clinical studies have suggested that rates of infusion-related reactions (IRRs) may be higher with amphotericin B colloidal dispersion (ABCD) versus other forms of amphotericin B. However, these studies did not permit the use of pre-medications upfront, which are now commonly used. Objectives To describe the use of pre-medications and determine the rate of IRRs in the real-world setting.

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