Protective effects of the combination of α-helical antimicrobial peptides and rifampicin in three rat models of Pseudomonas aeruginosa infection | Zendy

Oscar Cirioni | Zendy; Carmela Silvestri | Zendy; Roberto Ghiselli | Zendy; Fiorenza Orlando | Zendy; Alessandra Riva | Zendy; Federico Mocchegiani | Zendy; Leonardo Chiodi | Zendy; Sefora Castelletti | Zendy; Eleonora Gabrielli | Zendy; Vittorio Saba | Zendy; Giorgio Scalise | Zendy; Andrea Giacometti | Zendy

Open Access

Protective effects of the combination of α-helical antimicrobial peptides and rifampicin in three rat models of Pseudomonas aeruginosa infection

Author(s) -

Oscar Cirioni,

Carmela Silvestri,

Roberto Ghiselli,

Fiorenza Orlando,

Alessandra Riva,

Federico Mocchegiani,

Leonardo Chiodi,

Sefora Castelletti,

Eleonora Gabrielli,

Vittorio Saba,

Giorgio Scalise,

Andrea Giacometti

Publication year - 2008

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkn393

Subject(s) - pseudomonas aeruginosa , rifampicin , microbiology and biotechnology , magainin , in vivo , antimicrobial , in vitro , antibiotics , chemistry , biology , antimicrobial peptides , bacteria , biochemistry , genetics

An experimental study has been performed to compare the in vitro activity and the in vivo efficacy of magainin II and cecropin A with or without rifampicin against control and multidrug-resistant Pseudomonas aeruginosa strains.

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