Open AccessStaphylococcus aureus mediastinitis and sternal osteomyelitis following median sternotomy in a rat model
Author(s) -
Yoav Barnea,
Yehuda Carmeli,
Boris Kuzmenko,
Shiri NavonVenezia
Publication year - 2008
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkn378
Subject(s) - mediastinitis , sternum , osteomyelitis , staphylococcus aureus , medicine , vancomycin , median sternotomy , surgery , biology , bacteria , genetics
Median sternotomy (MS) wound infections are severe complications causing high morbidity and mortality after cardiac surgery. We aimed to develop a new Staphylococcus aureus mediastinitis and sternal osteomyelitis model in rats that can be used to evaluate the efficacy of new antimicrobial treatments.
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