Open AccessDevelopment and validation of a reversed-phase high-performance liquid chromatography assay for polymyxin B in human plasma
Author(s) -
Guoying Cao,
F. E. A. Ali,
F. Chiu,
Alexandre Prehn Zavascki,
Roger L. Nation,
Jian Li
Publication year - 2008
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkn343
Subject(s) - chromatography , high performance liquid chromatography , polymyxin b , polymyxin , derivatization , chemistry , reproducibility , detection limit , chloroformate , antibacterial agent , antibiotics , biochemistry
The purpose of this study was to develop a specific, sensitive, accurate and reproducible high-performance liquid chromatographic (HPLC) method to measure polymyxin B in human plasma.
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