Open AccessNatural D240G Toho-1 mutant conferring resistance to ceftazidime: biochemical characterization of CTX-M-43
Author(s) -
Giuseppe Celenza,
Carla Luzi,
Massimiliano Aschi,
Bernardetta Segatore,
Domenico Setacci,
Cristina Pellegrini,
Chiara Forcella,
Gianfranco Amicosante,
Mariagrazia Perilli
Publication year - 2008
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkn339
Subject(s) - ceftazidime , mutant , microbiology and biotechnology , biology , chemistry , bacteria , biochemistry , pseudomonas aeruginosa , gene , genetics
The aim of this article is biochemical and kinetic characterization of CTX-M-43, a natural Asp-240-->Gly mutant of CTX-M-44 (ex Toho-1), from a clinical isolate of Acinetobacter baumannii isolated in a Bolivian hospital.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom