HIV-2 integrase gene polymorphism and phenotypic susceptibility of HIV-2 clinical isolates to the integrase inhibitors raltegravir and elvitegravir in vitro | Zendy

Bénédicte Roquebert | Zendy; Florence Damond | Zendy; Gilles Collin | Zendy; Sophie Matheron | Zendy; G. Peytavin | Zendy; Antoine Bénard | Zendy; P. Campa | Zendy; Geneviève Chêne | Zendy; F. Brun-Vézinet | Zendy; Diane Descamps | Zendy

Open Access

HIV-2 integrase gene polymorphism and phenotypic susceptibility of HIV-2 clinical isolates to the integrase inhibitors raltegravir and elvitegravir in vitro

Author(s) -

Bénédicte Roquebert,

Florence Damond,

Gilles Collin,

Sophie Matheron,

G. Peytavin,

Antoine Bénard,

P. Campa,

Geneviève Chêne,

F. Brun-Vézinet,

Diane Descamps

Publication year - 2008

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkn335

Subject(s) - raltegravir , elvitegravir , integrase , integrase inhibitor , virology , human immunodeficiency virus (hiv) , biology , genetics , phenotype , gene , antiretroviral therapy , viral load

We investigated the in vitro phenotypic susceptibility of HIV-2 isolates from integrase inhibitor (INI)-naive patients to INIs and its relation to HIV-2 integrase gene polymorphism.

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