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Antimicrobial efficacy of chlorhexidine digluconate alone and in combination with eucalyptus oil, tea tree oil and thymol against planktonic and biofilm cultures of Staphylococcus epidermidis
Author(s) -
T.J. Karpanen,
T. Worthington,
Emma Hendry,
Barbara R. Conway,
Peter A. Lambert
Publication year - 2008
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkn325
Subject(s) - tea tree oil , antimicrobial , staphylococcus epidermidis , chlorhexidine , thymol , biofilm , microbiology and biotechnology , eucalyptus oil , eucalyptus , essential oil , traditional medicine , biology , staphylococcus aureus , chemistry , bacteria , medicine , food science , botany , dentistry , immunology , genetics
Effective skin antisepsis and disinfection of medical devices are key factors in preventing many healthcare-acquired infections associated with skin microorganisms, particularly Staphylococcus epidermidis. The aim of this study was to investigate the antimicrobial efficacy of chlorhexidine digluconate (CHG), a widely used antiseptic in clinical practice, alone and in combination with tea tree oil (TTO), eucalyptus oil (EO) and thymol against planktonic and biofilm cultures of S. epidermidis.

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