Antimicrobial activity of cefepime and rifampicin in cerebrospinal fluid in vitro | Zendy

Robert Sauermann | Zendy; Richard Schwameis | Zendy; Manfred Fille | Zendy; M. L. Camuz Ligios | Zendy; Markus Zeitlinger | Zendy

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Antimicrobial activity of cefepime and rifampicin in cerebrospinal fluid in vitro

Author(s) -

Robert Sauermann,

Richard Schwameis,

Manfred Fille,

M. L. Camuz Ligios,

Markus Zeitlinger

Publication year - 2008

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkn312

Subject(s) - cefepime , antimicrobial , antibiotics , cerebrospinal fluid , rifampicin , microbiology and biotechnology , staphylococcus aureus , pharmacology , medicine , biology , bacteria , imipenem , antibiotic resistance , genetics

Though used for infections of the central nervous system, the pharmacodynamics of antimicrobial agents is commonly evaluated only in commercially available bacterial growth media. In the present study, the effects of cerebrospinal fluid (CSF) on bacterial killing by cefepime and rifampicin were investigated.

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