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Aminocandin is an investigational echinocandin with excellent activity against Candida species, including Candida albicans and Candida tropicalis. However, few data are available for this agent versus Candida glabrata. We compared the in vitro potency and in vivo efficacy of aminocandin and caspofungin against clinical isolates of C. glabrata including those with reduced caspofungin susceptibility (MIC &gt; 2 mg/L).

Evaluation of aminocandin and caspofungin against Candida glabrata including isolates with reduced caspofungin susceptibility