Open AccessCefuroxime non-susceptibility in multidrug-resistant Klebsiella pneumoniae overexpressing ramA and acrA and expressing ompK35 at reduced levels
Author(s) -
Owe Källman,
A. Motakefi,
Bengt Wretlind,
M. Kalin,
B Olsson-Liljequist,
Christian G. Giske
Publication year - 2008
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkn296
Subject(s) - cefuroxime , klebsiella pneumoniae , multiple drug resistance , microbiology and biotechnology , klebsiella , enterobacteriaceae , medicine , biology , antibiotics , escherichia coli , gene , genetics
The aims were to study if efflux and down-regulation of porins contribute to cefuroxime resistance in Klebsiella pneumoniae and to co-resistance to unrelated antibiotics.
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