Once- or twice-daily dosing of nevirapine in HIV-infected adults: a population pharmacokinetics approach | Zendy

José Moltó | Zendy; Marta Valle | Zendy; C Miranda | Zendy; Samandhy Cedeño | Zendy; José LópezMiranda | Zendy; José Ramón Santos | Zendy; Eugènia Negredo | Zendy; J. Vilaro | Zendy; Joan CostaFont | Zendy; Bonaventura Clotet | Zendy

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Once- or twice-daily dosing of nevirapine in HIV-infected adults: a population pharmacokinetics approach

Author(s) -

José Moltó,

Marta Valle,

C Miranda,

Samandhy Cedeño,

José LópezMiranda,

José Ramón Santos,

Eugènia Negredo,

J. Vilaro,

Joan CostaFont,

Bonaventura Clotet

Publication year - 2008

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkn268

Subject(s) - nevirapine , dosing , pharmacokinetics , medicine , regimen , population , pharmacology , population pharmacokinetics , human immunodeficiency virus (hiv) , nonmem , trough concentration , virology , antiretroviral therapy , viral load , environmental health

The aim of this study was to develop and validate a population pharmacokinetic model for nevirapine in a population of HIV-infected adults and to evaluate the influence of nevirapine dosing regimen and patient characteristics on nevirapine trough concentration.

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