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Long-term clinical and surrogate marker effects of subcutaneous intermittent interleukin-2 without antiretroviral therapy in HIV-infected patients
Author(s) -
Christian Herzmann,
Zoe Cuthbertson,
Lisa Fosdick,
Martin Fisher,
Mark Nelson,
Nicky Perry,
Matthew Law,
Handan Wand,
George Janossy,
Margaret Johnson,
M Youle
Publication year - 2008
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkn238
Subject(s) - medicine , discontinuation , adverse effect , gastroenterology , antiretroviral therapy , cohort , immunology , surgery , human immunodeficiency virus (hiv) , viral load
Subcutaneous administration of interleukin-2 (IL-2) has been shown to increase CD4 counts in HIV-infected patients. It remains unclear whether this effect is associated with a clinical benefit.

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