Impact of depression on HIV outcomes in the HAART era | Zendy

Joshua D. Hartzell | Zendy; I. E. Janke | Zendy; Amy Weintrob | Zendy

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Impact of depression on HIV outcomes in the HAART era

Author(s) -

Joshua D. Hartzell,

I. E. Janke,

Amy Weintrob

Publication year - 2008

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkn193

Subject(s) - medicine , depression (economics) , human immunodeficiency virus (hiv) , viral load , mental health , substance abuse , ethnic group , lentivirus , antiretroviral therapy , immunology , psychiatry , viral disease , sociology , anthropology , economics , macroeconomics

Highly active antiretroviral therapy (HAART) has significantly decreased the morbidity and mortality of persons infected with HIV. The extent of the benefits, however, is not uniform, and certain factors including ethnicity, gender, baseline HIV viral load and CD4+ T lymphocyte count, adherence and intravenous drug abuse are associated with different immunological, virological and clinical outcomes. Mental health illness (MHI) and specifically depression may be associated with worse outcomes, although studies exploring the impact of MHI on HIV outcomes in both the pre-HAART and post-HAART eras have shown mixed results. The objective of the current paper is to review the available literature on the impact of MHI on HIV outcomes in the HAART era.

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