Efficacy and pharmacodynamics of linezolid, alone and in combination with rifampicin, in an experimental model of methicillin-resistant Staphylococcus aureus endocarditis | Zendy

Θωμάς Τσαγανός | Zendy; Ioannis Skiadas | Zendy; Pantelis Koutoukas | Zendy; Theodoros Adamis | Zendy; Nikolaos Baxevanos | Zendy; IraMaria Tzepi | Zendy; Αιμιλία Πελεκάνου | Zendy; Evangelos J. GiamarellosBourboulis | Zendy; Helen Giamarellou | Zendy; K. Kanellakopoulou | Zendy

Open Access

Efficacy and pharmacodynamics of linezolid, alone and in combination with rifampicin, in an experimental model of methicillin-resistant Staphylococcus aureus endocarditis

Author(s) -

Θωμάς Τσαγανός,

Ioannis Skiadas,

Pantelis Koutoukas,

Theodoros Adamis,

Nikolaos Baxevanos,

IraMaria Tzepi,

Αιμιλία Πελεκάνου,

Evangelos J. GiamarellosBourboulis,

Helen Giamarellou,

K. Kanellakopoulou

Publication year - 2008

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkn180

Subject(s) - linezolid , rifampicin , staphylococcus aureus , endocarditis , pharmacodynamics , medicine , methicillin resistant staphylococcus aureus , antibiotics , microbiology and biotechnology , vancomycin , staphylococcal infections , pharmacology , biology , pharmacokinetics , bacteria , genetics

To evaluate the efficacy of oral linezolid, with or without rifampicin, on valve vegetations and secondary foci of infection compared with vancomycin, in the absence or presence of rifampicin, in experimental endocarditis caused by methicillin-resistant Staphylococcus aureus.

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