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Persistence of PCR-positive tissue in benznidazole-treated mice with negative blood parasitological and serological tests in dual infections with Trypanosoma cruzi stocks from different genotypes
Author(s) -
Helen Rodrigues Martins,
Luísa M. Figueiredo,
J. C. O. Valamiel-Silva,
Cláudia Martins Carneiro,
George Luiz Lins Machado-Coelho,
Danielle Marquete Vitelli-Avelar,
Maria Terezinha Bahia,
Olindo Assis MartinsFilho,
Andréa Mara Macedo,
Marta de Lana
Publication year - 2008
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkn092
Subject(s) - benznidazole , serology , trypanosoma cruzi , chagas disease , genotype , biology , immunology , persistence (discontinuity) , virology , medicine , antibody , parasite hosting , gene , biochemistry , geotechnical engineering , world wide web , computer science , engineering
To assess different methodologies to better define an early post-therapeutic cure criterion after benznidazole treatment in BALB/c mice following mixed infection with dual Trypanosoma cruzi genotypes.

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