Antimicrobial activity of lupulone against Clostridium perfringens in the chicken intestinal tract jejunum and caecum | Zendy

Gregory R. Siragusa | Zendy; Gerhard Haas | Zendy; Paul D. Matthews | Zendy; Robert J. Smith | Zendy; R.J. Buhr | Zendy; Nick Dale | Zendy; Mark G. Wise | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Antimicrobial activity of lupulone against Clostridium perfringens in the chicken intestinal tract jejunum and caecum

Author(s) -

Gregory R. Siragusa,

Gerhard Haas,

Paul D. Matthews,

Robert J. Smith,

R.J. Buhr,

Nick Dale,

Mark G. Wise

Publication year - 2008

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkn024

Subject(s) - clostridium perfringens , caecum , jejunum , microbiology and biotechnology , antimicrobial , ileum , medicine , clostridium , clostridiaceae , clostridium infections , clostridiales , biology , antibiotics , clostridium difficile , bacteria , toxin , genetics

Owing to the spread of antibiotic resistance among human infectious agents, there is a need to research antibiotic alternatives for use in animal agricultural systems. Antibiotic-free broiler chicken production systems are known to suffer from frequent outbreaks of necrotic enteritis due in part to pathogenic type A Clostridium perfringens. Hop (Humulus lupulus) bitter acids are known to possess potent antimicrobial activity. Lupulone was evaluated for in vivo antimicrobial activity to inhibit C. perfringens in a chick gastrointestinal colonization model.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research