Foggy D-shaped zone of inhibition in Staphylococcus aureus owing to a dual character of both inducible and constitutive resistance to macrolide–lincosamide–streptogramin B | Zendy

Eun-Jeong Yoon | Zendy; AeRan Kwon | Zendy; Yu-Hong Min | Zendy; EungChil Choi | Zendy

Open Access

Foggy D-shaped zone of inhibition in Staphylococcus aureus owing to a dual character of both inducible and constitutive resistance to macrolide–lincosamide–streptogramin B

Author(s) -

Eun-Jeong Yoon,

AeRan Kwon,

Yu-Hong Min,

EungChil Choi

Publication year - 2008

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkn008

Subject(s) - biology , lincosamides , gene , genetics , microbiology and biotechnology , plasmid , staphylococcus aureus , bacteria

We identified Staphylococcus aureus strains having blunt inhibitory zones around the clindamycin or josamycin discs proximal to the erythromycin disc filled with slight bacterial growth. This ambiguous phenotype was termed as 'macrolide-lincosamide-streptogramin B antimicrobial (MLS(B)) resistance having a foggy D-shaped inhibitory zone' (fMLS(B)), and we tried to analyse its molecular mechanisms.

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