Open AccessAzithromycin alters macrophage phenotype
Author(s) -
Brian S. Murphy,
Vidya Sundareshan,
Theodore J. Cory,
Don Hayes,
Michael Anstead,
David J. Feola
Publication year - 2008
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkn007
Subject(s) - azithromycin , phenotype , macrophage , medicine , biology , microbiology and biotechnology , immunology , antibiotics , genetics , in vitro , gene
To investigate the in vitro effects of azithromycin on macrophage phenotype. Utilizing a mouse macrophage cell line (J774), we examined the effect of azithromycin on the properties that define classical macrophage activation (M1) and alternative macrophage activation (M2).
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