16S ribosomal RNA methylase RmtD produced by Klebsiella pneumoniae in Brazil | Zendy

Kunikazu Yamane | Zendy; F. Rossi | Zendy; M. G. M. A. Barberino | Zendy; Jennifer AdamsHaduch | Zendy; Yohei Doi | Zendy; David L. Paterson | Zendy

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16S ribosomal RNA methylase RmtD produced by Klebsiella pneumoniae in Brazil

Author(s) -

Kunikazu Yamane,

F. Rossi,

M. G. M. A. Barberino,

Jennifer AdamsHaduch,

Yohei Doi,

David L. Paterson

Publication year - 2008

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkm526

Subject(s) - ribosome , klebsiella pneumoniae , ribosomal rna , 16s ribosomal rna , 30s , microbiology and biotechnology , biology , rna , 5.8s ribosomal rna , peptidyl transferase , bacteria , biochemistry , escherichia coli , genetics , gene

Aminoglycosides are bactericidal agents that are used in the treatment of life-threatening infections caused by Gram-negative pathogens. They exert their antibacterial property by blocking the peptide bond-forming translocation process through binding to the aminoacyl site (A-site) of the 16S ribosomal RNA (rRNA) that constitutes the bacterial 30S ribosome.

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