Open AccessUnexpected antimicrobial effect of statins
Author(s) -
Susie Jerwood,
Jonathan Cohen
Publication year - 2007
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkm496
Subject(s) - antimicrobial , fluvastatin , medicine , simvastatin , vancomycin , staphylococcus aureus , linezolid , pharmacology , statin , microbiology and biotechnology , biology , bacteria , genetics
Epidemiological studies of statins have suggested a link between statin therapy and a decreased risk of sepsis. It has been proposed that the mechanism underlying this apparent protective effect of statins relates to their known immunomodulatory and anti-inflammatory effects. The aim of this study was to explore the antimicrobial effect of statins.
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