Prevalence and characterization of macrolide-lincomycin-streptogramin B-resistant Staphylococcus aureus in Korean hospitals | Zendy

Y.-H. Jung | Zendy; Ki Woong Kim | Zendy; K. M. Lee | Zendy; Jae Il Yoo | Zendy; G. T. Chung | Zendy; B. S. Kim | Zendy; Hyo Sun Kwak | Zendy; Youngsun Lee | Zendy

Open Access

Prevalence and characterization of macrolide-lincomycin-streptogramin B-resistant Staphylococcus aureus in Korean hospitals

Author(s) -

Y.-H. Jung,

Ki Woong Kim,

K. M. Lee,

Jae Il Yoo,

G. T. Chung,

B. S. Kim,

Hyo Sun Kwak,

Youngsun Lee

Publication year - 2007

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkm483

Subject(s) - lincomycin , plasmid , staphylococcus aureus , microbiology and biotechnology , antibiotics , biology , medicine , bacteria , gene , genetics

DHA-1 is an inducible plasmid-mediated AmpC b-lactamase whose emergence raises concerns because the mortality of patients infected with organisms that produce DHA-1 has been shown to be higher than that of patients infected with organisms that produce CMY-1. In conclusion, we have demonstrated that plasmid-mediated AmpC b-lactamases have emerged in Switzerland. The prevalence of 0.16% is still low. However, the occurrence of DHA-1, an inducible type of enzyme, raises clinical concerns. Additionally, a novel plasmid-mediated AmpC b-lactamase, which was designated CMY-31, was found.

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