Fitness and dissemination of disinfectant-selected multiple-antibiotic-resistant (MAR) strains of Salmonella enterica serovar Typhimurium in chickens
Author(s) -
Luke Randall,
Mary C. Bagnall,
Kimon Andreas Karatzas,
N. C. Coldham,
Laura J. V. Piddock,
Martin J. Woodward
Publication year - 2007
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkm415
Subject(s) - salmonella enterica , salmonella , microbiology and biotechnology , biology , serotype , antibiotics , disinfectant , strain (injury) , antibiotic resistance , mutant , bacteria , gene , medicine , genetics , pathology , anatomy
The aims of this study were to determine whether strains of Salmonella enterica serovar Typhimurium which had acquired low-level multiple antibiotic resistance (MAR) through repeated exposure to farm disinfectants were able to colonize and transmit between chicks as easily as the parent strain and, if such strains were less susceptible to fluoroquinolones, would high-level resistance be selected after fluoroquinolone treatment.
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