Elevated gatifloxacin and reduced rifampicin concentrations in a single-dose interaction study amongst healthy volunteers
Author(s) -
Helen McIlleron,
Jennifer Norman,
Thomas P. Kanyok,
P. Bernard Fourie,
John Horton,
Peter J. Smith
Publication year - 2007
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkm393
Subject(s) - gatifloxacin , rifampicin , pyrazinamide , isoniazid , pharmacology , medicine , drug interaction , drug , antibiotics , tuberculosis , levofloxacin , microbiology and biotechnology , biology , pathology
Pharmacokinetic drug-drug interactions were investigated between the fluoroquinolone gatifloxacin and a fixed dose combination (FDC) of rifampicin, isoniazid and pyrazinamide.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom