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Elevated gatifloxacin and reduced rifampicin concentrations in a single-dose interaction study amongst healthy volunteers
Author(s) -
Helen McIlleron,
Jennifer Norman,
Thomas P. Kanyok,
P. Bernard Fourie,
John Horton,
Peter J. Smith
Publication year - 2007
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkm393
Subject(s) - gatifloxacin , rifampicin , pyrazinamide , isoniazid , pharmacology , medicine , drug interaction , drug , antibiotics , tuberculosis , levofloxacin , microbiology and biotechnology , biology , pathology
Pharmacokinetic drug-drug interactions were investigated between the fluoroquinolone gatifloxacin and a fixed dose combination (FDC) of rifampicin, isoniazid and pyrazinamide.

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