Open AccessSpontaneous mutation frequency and emergence of ciprofloxacin resistance in Campylobacter jejuni and Campylobacter coli
Author(s) -
M.-L. Hanninen,
Markku S. Hannula
Publication year - 2007
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkm345
Subject(s) - campylobacter jejuni , campylobacter , ciprofloxacin , microbiology and biotechnology , campylobacter coli , biology , bacteria , antibiotics , genetics
We analysed the contribution of spontaneous mutation frequency to the evolution of ciprofloxacin resistance and the diversity of mutations in the quinolone resistance-determining region (QRDR) of gyrA and in the intergenic region, cmeR-cmeA, of the CmeABC efflux pump in Campylobacter jejuni and Campylobacter coli.
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