Effect of GrlA mutation on the development of quinolone resistance in Staphylococcus aureus in an in vitro pharmacokinetic model | Zendy

Yoshimi Oonishi | Zendy; Junichi Mitsuyama | Zendy; KYOKO YAMAGUCHI | Zendy

Open Access

Effect of GrlA mutation on the development of quinolone resistance in Staphylococcus aureus in an in vitro pharmacokinetic model

Author(s) -

Yoshimi Oonishi,

Junichi Mitsuyama,

KYOKO YAMAGUCHI

Publication year - 2007

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkm344

Subject(s) - levofloxacin , ciprofloxacin , staphylococcus aureus , population , pharmacology , quinolone , pharmacokinetics , mutant , microbiology and biotechnology , dosing , pharmacodynamics , antibiotics , chemistry , antibacterial agent , medicine , biology , bacteria , biochemistry , genetics , environmental health , gene

To investigate the effect of GrlA mutation on the development of quinolone resistance in Staphylococcus aureus in an in vitro pharmacokinetic (PK) model and to examine the relationship between the emergence of resistance and PK/pharmacodynamic parameters.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research