The Candida glabrata putative sterol transporter gene CgAUS1 protects cells against azoles in the presence of serum | Zendy

Hironobu Nakayama | Zendy; Koichi Tanabe | Zendy; Martin Bard | Zendy; Wayne C. Hodgson | Zendy; Sijia Wu | Zendy; D. Takemori | Zendy; Toshihiro Aoyama | Zendy; N. Selvamuthu Kumaraswami | Zendy; Laurel J. Metzler | Zendy; Yukie Takano | Zendy; Hiroji Chibana | Zendy; Masakazu Niimi | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

The Candida glabrata putative sterol transporter gene CgAUS1 protects cells against azoles in the presence of serum

Author(s) -

Hironobu Nakayama,

Koichi Tanabe,

Martin Bard,

Wayne C. Hodgson,

Sijia Wu,

D. Takemori,

Toshihiro Aoyama,

N. Selvamuthu Kumaraswami,

Laurel J. Metzler,

Yukie Takano,

Hiroji Chibana,

Masakazu Niimi

Publication year - 2007

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkm321

Subject(s) - azole , sterol , fluconazole , itraconazole , candida glabrata , biology , microbiology and biotechnology , transporter , tetracycline , ergosterol , atp binding cassette transporter , gene , pharmacology , cholesterol , biochemistry , candida albicans , antibiotics , antifungal

The uptake of endogenous sterol from serum may allow Candida glabrata to survive azole treatment. This study aims to determine the contribution of a sterol transporter that alters fluconazole sensitivity in the presence of serum.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research